Memorable dining experiences amidst the COVID-19 pandemic

Purpose: This study aims to investigate the effects of memorable dining experiences (MDEs) in the USA during the COVID-19 pandemic. Design/methodology/approach: A total of 530 valid survey responses were collected in the USA. Partial least squares structural equation modeling (PLS-SEM) was used to estimate inner and outer models. A two-stage approach was applied to test the moderating effects of restaurant safety measures. Additional analyses were conducted to compare electronic word of mouth (eWOM) intention and actual eWOM behavior. Findings: All five dimensions contributed to the overall memorability of a dining experience, with affect being the primary factor. Overall memorability was positively related to subjective well-being and actual eWOM behavior. Restaurant safety measures were positively related to the overall experience but did not moderate the relationship between any dimension and overall memorability. Research limitations/implications: Findings provide empirical support for the conceptualization of MDEs during a pandemic and underscore the importance of actual eWOM behavior in restaurant research. Practical implications: Results offer guidance for restaurant managers in designing MDEs. Originality/value: The restaurant industry is evolving from simply providing products and services to creating experiences. Yet the impacts of crafting MDEs are not well understood, especially during a pandemic. This study filled this gap by investigating MDEs and their effects on subjective well-being and eWOM behavior.

Partnership in Social Work Education Along the New Silk Road: Towards a Transformative Cultural Inclusion Model

We live in a world of disruption aggravated by the COVID-19 pandemic. In view of the highly divisive global discourse, we envision a different way of regional and international partnership in social work education and practice through our proactive partnership, to build hope and transformation. Social work educators from the Chinese Mainland, Hong Kong SAR, Kazakhstan, South Korea, Israel, and Vietnam, who have developed partnerships with counterparts in the countries along the New Silk Road, have come together to reflect on their partnership experiences, having developed the "Transformative Cultural Inclusion Model” consisting of four essential pillars: (1) equal partnership, (2) cultural inclusion, (3) capacity-building, and (4) social solidarity. Social work is a catalyst for social change and development, and we hope that the model can provide insights and principles to guide future development of regional and international partnerships. This will, in turn, develop context-specific authentic social work theories and practice by partnering together, engaging in participatory practice research, and making positive changes through education, research, and action with regional, international, and local partners. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

Revenge buying after the lockdown: Based on the SOR framework and TPB model

With the end of the pandemic and the lifting of the lockdown, the consumer market experienced revenge buying. The purpose of this study is to investigate the causes of revenge buying using the stimulus-organ-response (SOR) framework and the theory of planned behavior (TPB) model. Structural equation modeling was used to analyze data collected from 350 residents of Shanghai, China, after the city's lockdown was lifted. The findings imply that perceived scarcity, perceived susceptibility, and social influence regarding the lockdown can stimulate in-dividuals' anxiety, inducing behavioral intentions and ultimately leading to revenge buying consumer behavior. Theoretically, this study provides a novel explanation of revenge buying behavior. Additionally, conclusions offer ramifications for management and implementation strategies for dealing with revenge buying after sudden disasters.

Quality control circle applied to improve the compliance rate of infection control and prevention measures for staff in the medical observation isolation area for overseas tourists

Objective To ensure the safety of both doctors and patients，we should strengthen the management of infection control in the medical observation isolation area for overseas tourists，and continuously improve the compliance rate of infection control prevention measures. Methods In Mar 2020，the domestic COVID-19 was under control，however the overseas epidemic began to spread. As a designated screening hospital for overseas tourists，to prevent the occurrence of nosocomial infections caused by imported cases from abroad，the department carried out quality control prevention circle activities with the theme of"improving the compliance rate of infection control and prevention measures for staff in the medical observation and isolation area of overseas passengers”and determined four countermeasures implementation plans based on current situation grasp，goal setting，cause analysis and countermeasure formulation. Results Compared before and after the implementation of QCC，the compliance rate of the prevention measures of the staff in the medical observation and quarantine area for overseas passengers was increased from 45.08% to 91.54%，and the difference was statistically significant（P<0.001）.The target achievement rate was 84.43%，and the progress rate was 108.85%. Conclusion The quality control circle activities can improve the compliance rate of infection control and prevention measures for staff in the medical observation quarantine area for overseas tourists，thereby ensuring the safety of patients and staff. © 2022 Fudan University. All rights reserved.

Asymmetric dynamic risk transmission between financial stress and monetary policy uncertainty: thinking in the post-covid-19 world

Considering the dramatically increasing impact of the COVID-19 outbreak on monetary policy and the uncertainty in the financial system, we aim to examine the dynamic asymmetric risk transmission between financial stress and monetary policy uncertainty. Our sample covers 30 years of data. We first employ the conventional Granger causality test to examine the average relationship between financial stress and monetary policy uncertainty, and the results cannot provide evidence of causality between them. However, from an asymmetric perspective, we further detect the strongly apparent existence of the asymmetric structure of causality between them. Finally, we conduct further research on the asymmetric impacts from a time-varying perspective. The time-varying test finds that this relationship can be influenced by major events, especially the dot-com bubble, the 2009 financial crisis, and the current COVID-19 pandemic. Thus, one can learn more information about the influencing mechanism between financial stress and monetary policy with our work, which may be beneficial for making better decisions in the future. © 2023, The Author(s).

Towards Federated COVID-19 Vaccine Side Effect Prediction

We propose FedCovid, a new federated learning system based on electronic health records (EHR), to predict COVID-19 vaccination side effects. Federated learning allows diverse data owners to work together to train machine learning models without sharing data, ensuring the privacy of EHR data. However, because EHR data is unique, directly using existing federated learning models may fail. The EHR data is diverse, with numerical and categorical characteristics as well as consecutive visits. Furthermore, each client's data size is unequal, and the data labels are skewed due to the small number of patients that experience serious side effects. We present an adaptive approach to fuse heterogeneous EHR data and apply data augmentation techniques working with a margin loss to overcome the data imbalance issue in the client model training to address both challenges simultaneously in FedCovid. We recommend that when the server is updated, the data size of each client be taken into account to lessen the impact of clients with small data volumes. Finally, in order to train a stable and successful federated learning model, we suggest a new ordinal training technique. Experiments on a real-world dataset reveal that the suggested model is effective at predicting COVID-19 vaccination adverse effects. The performance increases by 14.35%, 17.81%, and 129.36% on the F1 score, Cohen's Kappa, and PR-AUC, respectively, compared with the best baseline (The source code of the proposed FedCovid is available at https://github.com/JackqqWang/FedCovid.git ). © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Quality control circle applied to improve the compliance rate of infection control and prevention measures for staff in the medical observation isolation area for overseas tourists

Objective To ensure the safety of both doctors and patients，we should strengthen the management of infection control in the medical observation isolation area for overseas tourists，and continuously improve the compliance rate of infection control prevention measures. Methods In Mar 2020，the domestic COVID-19 was under control，however the overseas epidemic began to spread. As a designated screening hospital for overseas tourists，to prevent the occurrence of nosocomial infections caused by imported cases from abroad，the department carried out quality control prevention circle activities with the theme of"improving the compliance rate of infection control and prevention measures for staff in the medical observation and isolation area of overseas passengers”and determined four countermeasures implementation plans based on current situation grasp，goal setting，cause analysis and countermeasure formulation. Results Compared before and after the implementation of QCC，the compliance rate of the prevention measures of the staff in the medical observation and quarantine area for overseas passengers was increased from 45.08% to 91.54%，and the difference was statistically significant（P<0.001）.The target achievement rate was 84.43%，and the progress rate was 108.85%. Conclusion The quality control circle activities can improve the compliance rate of infection control and prevention measures for staff in the medical observation quarantine area for overseas tourists，thereby ensuring the safety of patients and staff. © 2022 Fudan University. All rights reserved.

Forecasting the Asian stock market volatility: Evidence from WTI and INE oil futures

This study investigates whether China's crude oil futures (INE) and West Texas Intermediate (WTI) markets hold valuable information for estimating the realized volatility of seven Asian stock markets. This study has several notable findings. First, China's oil futures can trigger forecast accuracy for three equity indices (Nikkei 225, NSEI, and FT Straits Times), whereas WTI helps forecast the volatility of the two indices (KSE 100 and KOSPI). Second, comparing China's crude oil futures with WTI's crude oil futures, we find that the former could be an effective indicator for all seven Asian stock markets during a high-volatility period, while WTI information is helpful in forecasting the volatility of the KSE 100, NSEI, and FT Strait Times during the low-volatility period. Further, information of both oil futures is ineffective for the Hang Seng and SSEC equity indices. Our results are robust in several robustness checks, including alternative evaluation methods, recursive window approach, and alternative realized measures, even during the COVID-19 pandemic.

Memorable dining experiences amidst the COVID-19 pandemic

Purpose: This study aims to investigate the effects of memorable dining experiences (MDEs) in the USA during the COVID-19 pandemic. Design/methodology/approach: A total of 530 valid survey responses were collected in the USA. Partial least squares structural equation modeling (PLS–SEM) was used to estimate inner and outer models. A two-stage approach was applied to test the moderating effects of restaurant safety measures. Additional analyses were conducted to compare electronic word of mouth (eWOM) intention and actual eWOM behavior. Findings: All five dimensions contributed to the overall memorability of a dining experience, with affect being the primary factor. Overall memorability was positively related to subjective well-being and actual eWOM behavior. Restaurant safety measures were positively related to the overall experience but did not moderate the relationship between any dimension and overall memorability. Research limitations/implications: Findings provide empirical support for the conceptualization of MDEs during a pandemic and underscore the importance of actual eWOM behavior in restaurant research. Practical implications: Results offer guidance for restaurant managers in designing MDEs. Originality/value: The restaurant industry is evolving from simply providing products and services to creating experiences. Yet the impacts of crafting MDEs are not well understood, especially during a pandemic. This study filled this gap by investigating MDEs and their effects on subjective well-being and eWOM behavior. © 2022, Emerald Publishing Limited.

[The differential diagnosis of pulmonary infiltrates in cancer patients during the outbreak of the 2019 novel coronavirus disease].

Objective: To investigate the principles of differential diagnosis of pulmonary infiltrates in cancer patients during the outbreak of novel coronavirus (2019-nCoV) by analyzing one case of lymphoma who presented pulmonary ground-glass opacities (GGO) after courses of chemotherapy. Methods: Baseline demographics and clinicopathological data of eligible patients were retrieved from medical records. Information of clinical manifestations, history of epidemiology, lab tests and chest CT scan images of visiting patients from February 13 to February 28 were collected. Literatures about pulmonary infiltrates in cancer patients were searched from databases including PUBMED, EMBASE and CNKI. Results: Among the 139 cancer patients who underwent chest CT scans before chemotherapy, pulmonary infiltrates were identified in eight patients (5.8%), five of whom were characterized with GGOs in lungs. 2019-nCoV nuclear acid testing was performed in three patients and the results were negative. One case was a 66-year-old man who was diagnosed with non-Hodgkin lymphoma and underwent CHOP chemotherapy regimen. His chest CT scan image displayed multiple GGOs in lungs and the complete blood count showed decreased lymphocytes. This patient denied any contact with confirmed/suspected cases of 2019-nCoV infection, fever or other respiratory symptoms. Considering the negative result of nuclear acid testing, this patient was presumptively diagnosed with viral pneumonia and an experiential anti-infection treatment had been prescribed for him. Conclusions: The 2019 novel coronavirus disease (COVID-19) complicates the clinical scenario of pulmonary infiltrates in cancer patients. The epidemic history, clinical manifestation, CT scan image and lab test should be taken into combined consideration. The 2019-nCoV nuclear acid testing might be applied in more selected patients. Active anti-infection treatment and surveillance of patient condition should be initiated if infectious disease is considered.

Study on the Knowledge, Attitude and Behavior of College Students in Guangxi Province, China during Covid-19 Pandemic

COVID-19 has rapidly spread through countries .This occurrence has resulted in a huge negative response from the general public;the media continuously disseminate information to keep everyone notified regarding this global pandemic state. Public education is considered one of the most important measures that might help control COVID-19. This research assessed COVID-19 knowledge, attitude, and behaviour among college students in Guangxi Province, China. A cross-sectional survey-based that was conducted online on March 16, 2020 to May 4, 2020 among College students from Guangxi Province, China. The electronic survey devised by the researchers includes four main segments relating to the profile of the participants, knowledge, attitude and behavior during the novel coronavirus pandemic. The study data revealed that the respondents had an adequate level of knowledge about the mode of transmission, symptoms and prevention strategies on COVID-19. The survey likewise illustrated an overall positive attitude and behavior toward these protective measures for the virus and its responses if an infection was contracted. Also, Majority of the students don't consider the virus as a stigma or hide it from medical specialists. They avoid the situation where they can get COVID-19 and chose to seek medical treatment or isolate themselves if needed. The current study showed enough knowledge, positive behaviour and moderate attitude towards COVID-19 among the students. This response indicates the impact of the official statement confirmed by the WHO about COVID-19 being a disease outbreak and the initiatives of the health officials to notify and educate the public regarding this pandemic. Nonetheless, most research participants displayed satisfactory responses to COVID-19 knowledge behaviour and attitudes, implying the effectiveness of the awareness campaigns. The findings of the study may prove to be the basis for preparing government programs, policies and plans to adequately manage COVID-19 and to limit its transmission. © 2021 Kriedt Enterprises Ltd. All right reserved.

Angiotensin-Converting Enzyme Receptor Genotype and its Activity Level as Potential Predictors of the Severity COVID-19 among Iraqi Patients

Objectives: The purpose of this study is to determine whether the angiotensin-converting enzyme activity and various biomarkers are used to investigate the severity of Covid-19 and to study the genetic variation occurs in angiotensin-converting enzyme-2 (ACE-2) receptor in severe Covid-19-related genes in the Iraqi population of Kerbala Province. Methods: This case-control study was conducted on 176 subjects who survived hospitalization and diagnosed by physician. Various biomarkers including ferritin, C-reactive protein, lactate dehydrogenase, alanine aminotransferase, aspartate aminotransferase, angiotensin-converting enzyme-2 activity levels were determined. Accordingly, they were divided into three groups: 59 of them were infected with severe Covid-19, 54 of them were infected with moderate Covid-19 and 63 of them were checked and obtained as apparently healthy control. Severe and moderate patients were collected from Al-Hayat tertiary center at AI-Hussein Medical City, Kerbala Health Directorates, Kerbala - Iraq during Oct., 2020-July, 2021 with matched age ranged between (23-88) years. Blood samples of apparently healthy and Covid-19 samples were subjected to genomic DNA extraction within 24-48 hours of aspi ration. The genomic DNA extracted was subjected to electrophoresis through 1.5% of agarose gels which was detected by staining with the fluorescent dye ethidium bromide and then visualized by illumination with UV light to confirm the presence and integrity of the extracted DNA. Results: Genotyping of ACE-2 (I/D) polymorphism (rs4646994), which has a high prevalence, was performed by polymerase chain reaction assay. The amplification of an Alu repetitive element in an intron of the ACE-2 has shown three potential genotypes of I/I and D/D as homozygous, and l/D as heterozygous. Individuals with normal homozygous (DD) revealed band of (190 bp), while individuals with normal (II) revealed band of (490 bp), and the individuals with heterozygous (ID) revealed two bands (190, 490 bp) respectively. Every severe Covid-19 group carried (DD) allele genotype, moderate group carried (ID and II) alleles and finally the control group carried (DD, ID, II) alleles genotype. Conclusion: In the ACE-2 polymorphism, the D/D genotype allele is implicated as a risk factor for severe Covid-19 patients, in Iraqi population.

Key factors driving customers' restaurant dining behavior during the COVID-19 pandemic

Purpose This study aims to identify key factors that affected US respondents' dining behavior at restaurants during the midst of the COVID-19 pandemic. Design/methodology/approach Due to the lack of a prior framework or model to test customers' perceptions of dining-out behavior during this unprecedented time, this study used a mixed-methods approach, conducting two focus group discussions to generate potential restaurant attributes, followed by a US-based survey using an online panel. Using structural equation modeling, this study tested eight developed propositions. Findings The findings of this study indicated that the three key factors (i.e. restaurant dining environment, communication and hygiene and contactless features) made customers feel comfortable dining in the restaurant during the pandemic. Out of these three factors, only the restaurant dining environment and communication and hygiene were essential predictors for customers' perceived trust toward the restaurant, leading to their willingness to pay more. This study used two moderators, customers' perceived risk and support for restaurants to examine how they affected customers' perceived trust and willingness to pay, respectively. Practical implications This study provides both theoretical and practical implications to the current body of knowledge in customers' dining-out behavior and the development of operational strategies for restaurants to accommodate customers' changing dining-out behavior due to the COVID-19 pandemic. To develop a holistic conceptual framework, this study incorporates two COVID-19-focused measurement items, perceived risk and support of the restaurant, to identify their moderating roles in the relationships among the five proposed measurement items. This study provides restaurant operators with insights into the altered dining-out behavior of their customers due to the COVID-19 pandemic and prepares them for the post pandemic environment. Originality/value During the unprecedented pandemic situation, few customers are willing to dine in restaurants. As local and national governments lifted the mandated COVID-19 protocols, restaurants opened their business slowly to cater to customers in compliance with the centers for disease control's health and safety regulations. It is of utmost importance for restaurant operators to accommodate their customers' needs when they dine in the middle of the COVID-19 pandemic. There is a paucity of research that has examined customers' comfort level when dining in restaurants and customers' preferred dining environment during the pandemic.

[Health management of breast cancer patients outside the hospital during the outbreak of 2019 novel coronavirus disease].

The outbreak of 2019 novel coronavirus disease (COVID-19) is spreading rapidly. In order to prevent cluster outbreaks, the government strengthened the management and control of personnel mobility, which had a great impact on the examination and treatment of breast cancer patients. This paper discusses how to realize scientific health management of breast cancer patients outside the hospital based on the existing epidemic situation, characteristics of breast cancer patients and public health safety factors. The breast cancer patients should synthetically consider the epidemic prevention situation of inhabitance, the disease stage and previous therapeutic schedule to decide the next therapeutic schedule. If necessary, after professional discussion and communication between doctors and patients online or offline, the hospital visiting time should be delayed through seeking alternative treatment schemes, and psychological counseling for patients should be paid attention to at the same time.

RC48-ADC, a HER2-targeting antibody-drug conjugate, in patients with HER2-positive and HER2-low expressing advanced or metastatic breast cancer: A pooled analysis of two studies

Background: Currently, there are no standard ≥3 line regimens recommended for HER2-positive (IHC 3+, or IHC 2+/FISH+) advanced or metastatic breast cancer, and no recommended HER2-targeting treatment for HER2-low expressing (IHC 2+/FISH-, or IHC 1+) population. RC48-ADC is an innovative HER2-targeting antibody-drug conjugate with a cleavable linker and a potent microtubule inhibitor payload MMAE that has a bystanding effect in tumor cell killing. Methods: C001 CANCER (NCT02881138) was a dose-escalation phase I study (0.5, 1.0, 1.5, 2.0, and 2.5 mg/kg) with the 3+3 design among HER2-positive patients. C003 CANCER (NCT03052634) was a phase Ib study with 1.5, 2.0, and 2.5 mg/kg doses in the HER2-positive subgroup and 2.0 mg/kg dose in both IHC 2+/FISH-, and IHC 1+ HER2-low expressing subgroup. C003 CANCER is currently ongoing for IHC 1+ patients. Pooled analysis of the two studies was conducted for the efficacy and safety of RC48-ADC in HER2-positive or HER2-low expressing subgroups. Results: At the time of data cutoff (December 31, 2020), 118 female breast cancer patients were enrolled and treated with RC48-ADC. 70 patients (59.3%) were HER2-positive and 48 patients (40.7%) were HER2-low expressing. At baseline, 77 patients (65.3%) had liver metastases, 50 patients (42.4%) were ECOG PS 1, 47 patients (39.8%) had received ≥3 prior chemotherapy regimens. In the HER2-positive subgroup, ORRs for 1.5, 2.0, and 2.5 mg/kg doses were 22.2% (95% CI: 6.4%, 47.6%), 42.9% (95% CI: 21.8%, 66.0%), and 40.0% (95% CI: 21.1%, 61.3%). mPFSs for 1.5, 2.0, and 2.5 mg/kg cohorts were 4.0 months (95% CI: 2.6, 7.6), 5.7 months (95% CI: 5.3, 8.4) and 6.3 months (95% CI: 4.3, 8.8). In the HER2-low expressing subgroup, the ORR and mPFS were 39.6% (95% CI: 25.8%, 54.7%) and 5.7 months (95% CI: 4.1, 8.3). ORR and mPFS for IHC2+/FISH-patients were 42.9% (15/35) and 6.6 months (95% CI: 4.1, 8.5). For IHC1+ patients, even though the COVID-19 pandemic led to treatment postpone for some patients, ORR and mPFS reached 30.8% (4/13) and 5.5 months (95% CI: 2.7, 11.0). The common treatmentrelated adverse events (TRAEs) were AST increased (64.4%), ALT increased (59.3%), hypoesthesia (58.5%), white blood cell count decreased (48.3%), and neutrophil count decreased (47.5%);most were grade 1-2 in severity. Neutrophil count decreased (16.9%), GGT increased (12.7%), and fatigue (11.9%) were the grade 3 and above TRAEs occurring in ≥ 10% of the overall population. Conclusions: RC48-ADC showed consistent efficacy in HER2-positive and HER2-low expressing subgroups. The 2.0 mg/kg Q2W showed a more favorable benefit-risk ratio than other dose levels. No new safety signals were observed. Further studies are initiated to evaluate the efficacy and safety of RC48-ADC in various settings.

Forecasting China's Crude Oil Futures Volatility: The Role of the Jump, Jumps Intensity, and Leverage Effect

This study explores the forecasting ability of jump, jump intensity, and leverage effect for an emerging futures market, China's crude oil futures market, using different kinds of HAR-type models. From an in-sample perspective, we find that the HAR components, monthly leverage effect, jump size, and jump intensity have positive effects on future oil volatility. Moreover, out-of-sample results show that a forecasting model with jump and jump intensity cannot only achieve a superior forecasting performance under low volatility level but also increase the economic value. Subsequently, we examine the effect of decompositions of jump information, the results show signed jump components can improve the accuracy. Finally, we extend our empirical analysis considering different forecast horizons, COVID-19 pandemic, and different trading hours. Our empirical results are robust and consistent. © 2020 John Wiley & Sons, Ltd.

[Surgical treatment strategy for digestive system malignancies during the outbreak of COVID-19].

The outbreak of COVID-19 occurred in Wuhan, Hubei province of China, at the end of 2019, and spread rapidly across the country. After the outbreak of this disease, the overwhelming majority of cities have launched the "first level response" and the regular diagnosis and treatment of cancer patients are greatly affected. The digestive systemic cancer is the most common malignancy. Most patients are diagnosed in the advanced stage with poor prognosis. The epidemic of COVID-19 poses new challenges to diagnosis and treatment of the patients with digestive system malignancies. Based on the fully understanding of the characteristics of digestive system tumors, we should change the treatment strategy and adopt more reasonable treatment strategy timely during the epidemic period to minimize the adverse effects of the epidemic of COVID-19 on the treatment.